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Branched-Chain Amino Acids

Amino Acid

Overview

  • Branched-Chain Amino Acids (BCAAs): A trio of essential amino acids—leucine, isoleucine, and valine—crucial for muscle growth, recovery, and energy production.
  • Supplementation Purpose: To provide readily available BCAAs, reducing muscle damage and soreness while promoting muscle protein synthesis and endurance during intense exercise.
  • Potential Benefits: Enhanced athletic performance, accelerated recovery, and improved overall muscle health.

Chemistry

  • Leucine: Molecular Formula: C₆H₁₃NO₂; IUPAC Name: (2S)-2-Amino-4-methylpentanoic acid; Key Features: Branched-chain structure with a methyl group (CH₃) on the fourth carbon, hydrophobic character.
  • Isoleucine: Molecular Formula: C₆H₁₃NO₂; IUPAC Name: (2S,3S)-2-Amino-3-methylpentanoic acid; Key Features: Branched-chain structure with a methyl group (CH₃) on the third carbon.
  • Valine: Molecular Formula: C₅H₁₁NO₂; IUPAC Name: (2S)-2-Amino-3-methylbutanoic acid; Key Features: Branched-chain structure with a methyl group (CH₃) on the third carbon.
  • Key Structural Features (all BCAAs): Branched-chain structure (hydrophobic), central alpha carbon bonded to an amino group (-NH₂), a carboxyl group (-COOH), and a side chain (R group) with a methyl group (CH₃).
  • Properties: Essential amino acids (cannot be synthesized by the human body).

Sources & Quality

  • Natural Sources: Animal-based foods (meat, poultry, fish, eggs, dairy), plant-based foods (legumes, beans, lentils, nuts), and grains (brown rice, quinoa, whole wheat—smaller amounts).
  • Extraction and Synthesis Methods: Fermentation (microorganisms), enzymatic hydrolysis (enzymes break down proteins), chemical synthesis, and recrystallization (purification).
  • Supplement Quality Considerations: Purity (high purity levels, e.g., 99% or higher), ratio (e.g., 2:1:1 Leucine:Isoleucine:Valine), source (reputable manufacturers), third-party testing (NSF International, Informed-Choice), label claims (accuracy), and manufacturing processes.

Where to Buy Branched-Chain Amino Acids

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