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Oz Ginkgo Biloba

Nootropics

Overview

  • Oz Ginkgo Biloba is a standardized botanical extract derived from the leaves of Ginkgo biloba L., a living fossil tree native to East Asia.
  • The supplement is formulated to deliver a standardized concentration of flavonoid glycosides and terpene lactones.
  • Its primary purpose is to support brain health and circulatory function in adults seeking to maintain cognitive performance and vascular tone.

Chemistry

  • The active fraction of Oz Ginkgo Biloba is a standardized extract containing:
    • Flavonoid glycosides (quercetin-3-O-glucoside, kaempferol-3-O-glucoside)
    • Terpene lactones (ginkgolide A, B, C, bilobalide)
  • Ginkgolides are sesquiterpene lactones with a unique bicyclic ring system (C₁₉H₂₄O₅ for ginkgolide A, IUPAC: (2S,3R,4S,5R,6S)-5,6-dihydroxy-3-(2-hydroxymethyl-5-hydroxy-4-methoxy-1-oxo-2-pyrrolidinyl)-4-methyl-2-pyrrolidine).
  • Bilobalide is a sesquiterpene lactone with formula C₁₅H₁₈O₈ (IUPAC: 4-(2-hydroxy-2-methylpropyl)-2-methyl-6-hydroxy-5-oxo-2-pyrrolidine).
  • The standardized extract typically contains:
    • 24 % flavonoid glycosides (expressed as quercetin equivalents)
    • 6 % terpene lactones (ginkgolides A–C and bilobalide)
  • The extract is water-ethanol-based, standardized to a minimum of 2.5 % ginkgolic acids (often reduced to <5 ppm) to minimize allergenic potential.

Sources & Quality

  • Oz Ginkgo Biloba is sourced primarily from mature Ginkgo biloba trees cultivated in China (Shandong, Zhejiang provinces) and Korea.
  • Leaves are harvested in late autumn when flavonoid concentrations peak.
  • Leaves are dried at ≤40 °C to preserve thermolabile constituents.
  • Extraction employs a 50 % ethanol-water mixture under controlled temperature (60 °C) and vacuum.
  • The extract is purified by resin-based chromatography to achieve the 24 %/6 % standardization.
  • The extract is tested for heavy metals, pesticide residues, and microbial load per USP <795> guidelines.
  • High-quality manufacturers employ:
    • GMP-certified facilities
    • Batch-to-batch HPLC fingerprinting
    • Third-party certification (e.g., USP, NSF) to ensure consistency and safety.

Where to Buy Oz Ginkgo Biloba

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